Ultrafiltration membrane: opening a new chapter in the purification of polysaccharide iron complexes

Polysaccharide iron complexes, as a new generation of iron supplements, have attracted much attention and are ideal drugs for treating iron deficiency anemia.

However, traditional techniques are inadequate for extracting polysaccharide iron complexes. The alcohol precipitation process is complex and accompanied by safety hazards, and the large amount of steam consumed during alcohol recovery results in high costs. Electrodialysis devices can easily cause colloidal particle aggregation, leading to pipeline blockage and membrane fouling. The chlorine gas generated during operation can also corrode the device. The two-step membrane process of nanofiltration technology is costly, and the retention of free iron ions also affects product purity. The lower filtration flux significantly increases investment costs.

The ultrafiltration membrane purification process of Jiuwu High Tech is like a magical key, accurately opening a new door for the purification of polysaccharide iron complexes.

The ultrafiltration membrane filtration process can be called the core "magic array". The pore size of ultrafiltration membrane components is between 2-50nm, with a molecular weight cut-off of 5K-150KDa. When the crude aqueous solution of polysaccharide iron complex enters this "magic circle", the wonderful separation begins. Polysaccharide iron complexes are firmly "captured" by ultrafiltration membranes due to their large molecular weight and gelatinous state, while small molecular impurities such as sodium chloride and free iron ions quietly leave along the permeate.   

Dialysis operation is a "divine assist" that adds icing on the cake. It can appear before and after ultrafiltration concentration. By adding water to the ultrafiltration membrane components and cleverly controlling the water addition rate to be consistent with the ultrafiltration membrane permeate flux, it can significantly reduce the concentration of sodium chloride to below 2% of the mass concentration, as if installing a precise impurity "cleaner" into the purification process.

The advantages of this process are fully demonstrated. Simple operation, no need for complex processes and equipment, making it easy for enterprises to get started; Safe and energy-saving, avoiding many risks and energy consumption traps of traditional processes; Mild conditions and gentle protection of the structure and properties of polysaccharide iron complexes; Easy to produce continuously, laying a solid foundation for large-scale output. Not only can it reduce salt concentration, but it can also increase polysaccharide iron concentration, with a polysaccharide iron recovery rate of over 95%, efficiently utilizing resources and bringing abundant benefits to enterprises.

For example, when processing the crude water solution of pumpkin polysaccharide iron complex, the concentration of sodium chloride in the ultrafiltration membrane retention solution decreased to 1.8% wt, the iron content significantly increased, free iron ions disappeared, and the recovery rate reached 98.8%. Numerous examples have shown that this ultrafiltration membrane purification process is reliable and excellent.

Jiuwu High Tech's technology has led the purification process towards a new journey of efficiency, precision, and environmental protection, leaving a brilliant chapter in the innovation of medicine.